Protective effect of standardized extract of Biophytum sensitivum against calcium oxalate urolithiasis in rats

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Effect of Aerva lanata on calcium oxalate urolithiasis in rats.

Calcium oxalate (CaOx) stone was induced in rats using 0.75% of ethylene glycol in drinking water for 28 days. Ethylene glycol treated rats showed significant increase in the activities of oxalate synthesizing enzymes such as glycolic acid oxidase (GAO) in liver and lactate dehydrogenase (LDH) in liver and kidney. CaOx crystal deposition, as indicated by increased excretion of stone-forming con...

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Immunomodulatory and antitumor activity of Biophytum sensitivum extract.

An alcoholic extract of Biophytum sensitivum was studied for its immunomodulatory and antitumor activity. The extract was 100% toxic at a concentration of 0.5 mg/ml to Dalton's lymphoma ascites (DLA) and Ehrlich ascites carcinoma (EAC) cells. B. sensitivum extract was also found to be cytotoxic towards L929 cells in culture at a concentration of 0.1 mg/ml. Administration of B. sensitivum extrac...

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Hypoglycemic effect of Biophytum sensitivum in the alloxan diabetic rabbits.

Hypoglycaemic effect of a Neapalese plant Biophytum sensitivum was investigated in the alloxan diabetic male rabbits of different severities: subdiabetic (Alloxan recovered; AR), mild diabetic (MD) and severely diabetic (SD). Assessment of activity of the extract, prepared from the plant leaves, was done by fall in fasting plasma glucose (FPG) and improvement in the oral glucose tolerance test ...

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Antibacterial activity of leaf extracts of Biophytum sensitivum (L.) DC

Biophytum sensitivum (L.) DC. (Oxalidaceae) is an ethnomedicinal plant used in folklore medicine. The main aim of this study demonstrates that the leaves extracts of B. sensitivum (methanol, chloroform, acetone, and petroleum ether) was evaluated for its antibacterial activity against several human pathogenic bacterial strains (Bacillus subtillis, Staphylococcus aureus, Streptococcus pneumonia,...

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ژورنال

عنوان ژورنال: Bulletin of Faculty of Pharmacy, Cairo University

سال: 2015

ISSN: 1110-0931

DOI: 10.1016/j.bfopcu.2015.10.002